The purpose of this communication is to announce the launch of a new program of research grant support for research by young investigators in multiple disciplines whose interests, career objectives and current training or employment situations enable them to embark on important new areas of research addressing the prevention, diagnosis, or treatment for persons with various forms of dementia, including Alzheimer’s disease, or research on programs for the care of persons with these conditions.  The program will accept applications for basic, translational, clinical or community-based care delivery research related to dementia.  Research projects will be accepted for review employing cellular, animal or human models.

Eligibility for Grant Support

The program will target young investigators (i.e., those who are less than 10 years beyond the beginning of any post-doctoral research training, and have not yet received major funding at the R01 level or who have not yet been recognized with tenure at their respective institutions) and who are affiliated with one of the four academic health centers in North Carolina (East Carolina University, Duke University, University of North Carolina at Chapel Hill, or Wake Forest University), plus the Jerry M. Wallace School of Osteopathic Medicine at Campbell University.

Applicants must have at least one senior faculty member (at the associate or full professor level) at their host institutions willing to serve as primary mentors for the applicant if they are awarded support under this program.  Primary mentors must be willing to serve in this capacity without compensation from these funds.  No more than half of the financial support from this program may be used for salary support for the applicant.  Applicants may not be post-doctoral fellows in the laboratory of a senior investigator at the time the grant is awarded or during the period in which support is provided under this program.



to East Carolina University (Brody School of Medicine) from Alzheimer’s North Carolina for A Multidisciplinary Approach to Fight Senior Dementia: the Wooten Laboratory for Alzheimer’s and Neurodegenerative Diseases Research. Qun Lu, PhD

to University of NC Wilmington, Department of Psychology for Research Project – Therapeutic Approaches to Regulate Neuroinflammation in Alzheimer’s Disease. Dr. Rachel Kohman

to Duke University from Alzheimer’s North Carolina for the Project – North Carolina Regional Consortium for Brain Health in Aging. Kathleen Welsh-Bohmer, PhD

to Brody School of Medicine East Carolina University from Alzheimer’s North Carolina for Part II of “A Multidisciplinary Approach to Fight Senior Dementia.”  Qun Lu, PhD

to Harriet & John Wooten Laboratory for Alzheimer’s and Neurodegenerative Diseases. Qun Lu, PhD

to Harriet & John Wooten Laboratory for Alzheimer’s and Neurodegenerative Diseases. Qun Lu, PhD

Two winners of the Lina Mae Edwards Young Investigator Research Grants:

Jessica M. Ellis, PhD, East Carolina University: Deciphering the Role of DHA in the Development of Brain Disorders
Daniel Parker, MD, Duke University: The Effect of Exercise Mode, Amount and Intensity on Plasma Markers of Brain Aging in Healthy Adults.


Research projects we fund cover four broad areas:

  • Prevention
  • Diagnosis
  • Treatment/service delivery/models of care/quality and cost of care/workforce
  • Caregiver support

Two-year awards will be granted with a maximum of $50,000 per year ($100,000 total per individual awarded).

  • Two awards will be made in the first year, followed by a second set of two awards in the second year, for a total financial allocation of $400,000.  Successful awardees will be expected to submit an annual report near the end of the initial year of funding, on the basis of which a second year of support would be forthcoming.
  • Awards will not cover payment of indirect costs.  If the total amount of the award is to be allocated to the salary support for the awardee, it is recommended that the proposal contain sufficient information to determine (on the basis of formal commitments from the host institution) that the research expenses of the proposed project could be completed during the time of the award of support from the Dementia Alliance of North Carolina.

Proposals are specifically invited from younger, early career investigators who will embark on studies using human subjects, preferably from North Carolina populations. All applicants should be full-time faculty (i.e. instructors or assistant professors who’ve not yet achieved academic tenure), all of whom are likely to still be in the pre-tenure stages of their careers throughout the term of the award they would receive from the Dementia Alliance of North Carolina.

  • Step One: Submission of Letters of Intent

Submission of letters of intent from prospective applicants, along with information describing the proposed focus of the research project, the credentials and position of the applicant at the host institution, the identity of the applicant’s mentor, and a brief description of the proposed study population.

  • Step Two (if applicants letter of intent is accepted): Submission of Full Proposal

Submission of full proposals must provide details about specific aims of the research, the study population(s), research methods, analysis plans and questions that might be addressed by the proposed research, a budget and narrative describing the direct and indirect costs associated with the project (and other funds that are likely to be needed or have already been acquired).  The proposed mentor for the applicant is expected to submit a letter describing his/her relationship with the applicant and specifying the extent to which he/she would be available to the applicant were the project to be funded by the Dementia Alliance of North Carolina.

Solicitations of proposals will be accepted from the five academic health centers/or medical schools in North Carolina.

  • East Carolina University Brody School of Medicine
  • Duke University
  • Campbell University School of Osteopathic Medicine
  • Wake Forest School of Medicine
  • University of North Carolina at Chapel Hill

In addition to the academic deans of these institutions, solicitations will be addressed to the respective chairs of the departments or divisions of family medicine, general internal medicine, geriatric medicine, neurology, allied health (physical therapy, occupational therapy, speech therapy), complementary medicine, nursing and social work.